Greenwood MD, et al. - In this randomized clinical trial involving 20 patients (40 eyes), researchers sought to determine the preference of patients undergoing bilateral LASIK for either the dexamethasone intracanalicular insert or topical prednisolone acetate for control of postoperative symptoms and ocular surface signs. One eye was randomized to receive the dexamethasone insert or topical prednisolone acetate 1% four times a day for a week and 2 times a day for a second week; alternative treatment was provided to the fellow eye. For postoperative treatment, patients undergoing elective bilateral femtosecond LASIK surgery overwhelmingly (by an 8-to-1 margin) preferred the dexamethasone insert to topical prednisolone acetate. The insert gave similar ocular comfort, corneal staining, and visual acuity outcomes to topical prednisolone. In this quality of life-conscious population, the insert is an appropriate means of postoperative symptom control.