Ruangkit C, et al. - In preterm infants of multiple births, researchers compared the outcomes of immediate cord clamping (ICC) vs delayed cord clamping (DCC). Women with multiple pregnancies, including twins and triplets with 28–36 weeks of gestational age, were randomized to receive ICC (23 women and 50 infants) or DCC for 30–60 s (24 and 51 infants). No significant differences were found between the groups in admission hematocrit, superior vena cava (SVC) flow measured within 24 h, hematocrit at 8 weeks of age, or any other neonatal outcomes. When compared with ICC, DCC for 30–60 s did not improve placental transfusion or increase systemic blood flow in multiple-birth infants born preterm, mostly by cesarean section (CS). The determination of a higher rate of postpartum hemorrhage (PPH) in the DCC group raises concerns about the maternal safety of this procedure in this patient population.