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A prudent dietary pattern is inversely associated with liver fat content among multi‐ethnic youth

Pediatric Obesity May 28, 2021

Perng W, Harte R, Ringham BM, et al. - This study was carried out to distinguish dietary patterns correlated with a hepatic fat fraction (HFF), a measure of liver fat content and a risk factor for non‐alcoholic fatty liver disease, in a prospective study of 397 multi‐ethnic youth. Via the Block Kids Food Frequency Questionnaire, researchers collected information on habitual dietary intake at age 6 to 15 years (‘T1’) and 12 to 19 years (‘T2’) and assessed HFF using magnetic resonance imaging at T2. Dietary patterns were derived via principal components analysis and explored relationships with ln‐transformed HFF using linear regression models that accounted for maternal education, gestational diabetes exposure, and smoking habits; and child pubertal status, BMI, and physical activity. It was shown that a diet high in fruits and vegetables is correlated with lower HFF, whereas a diet high in fried foods and refined carbohydrates is related to higher HFF even in healthy youth. The results illustrated that dietary changes may serve as an early preventive measure to mitigate liver fat accrual.

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