A prospective observational study on the stress levels at the time of embryo transfer and pregnancy testing following in-vitro fertilization Treatment: A comparison between women with different treatment outcome
BJOG: An International Journal of Obstetrics and Gynaecology Aug 17, 2018
Cheung CWC, et al. - Via performing a prospective observational study, researchers sought for the role of stress biomarker and psychological indices of stress in predicting both conception and miscarriage rates in women undergoing in-vitro fertilization/ intracytoplasmic sperm injection (IVF/ ICSI). They recruited 197 subjects to (1) completed validated psychological questionnaires (visual analogue scale of stress, state trait anxiety inventory, perceived stress scale, fertility problem Inventory, Beck depression inventory, and general health questionnaire), at the time of embryo transfer (ET) and pregnancy testing (PT), and (2) provided saliva samples for alpha amylase (sAA) measurement before and after ET and at PT. Following ET, they noted the highest sAA level, while psychological stress was identified highest at PT. However, conception or miscarriage seemed not to be predicted using either of the stress level.
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