Repici A, et al. - Given that SIC-8000 (Eleview) is a new FDA-approved solution for submucosal injection developed to provide a long-lasting cushion to facilitate endoscopic resection maneuvers, the researchers compared the efficacy and safety of SIC-8000 with those of saline solution, when performing endoscopic mucosal resection (EMR) of large colorectal lesions. The results obtained from this randomized double-blind trial indicate that a new FDA approved agent for sub-mucosal injection seemed to be a more powerful and equally safe submucosal agent for EMR injection than saline solution.