Wang G, Tang WY, Wills-Karp M, et al. - Researchers here investigated if and how prenatal Mn concentrations associate with the risk of elevated BP at ages 3–12 y. For this analysis, a total of 1,268 mother-child dyads were enrolled at birth and followed prospectively at the Boston Medical Center. Using inductively coupled plasma mass spectrometry on RBCs collected within 1–3 d after delivery (reflecting late-pregnancy Mn exposure), the median (IQR) maternal RBC Mn concentration of 37.5 (29.2–48.5) μg/L was identified. Elevated BP rate of 25% was observed among children at ages 3–12 y. Risk of elevated BP was higher among children aged 6–12 y in correlation with both the lowest and highest quartiles of maternal RBC Mn concentrations compared with those in the second and third quartiles. Findings thereby suggest a nonlinear correlation between maternal RBC Mn concentrations and raised BP among children aged 6–12 y from a high-risk, predominantly minority population