Inker LA, Couture SJ, Tighiouart H, et al. - It is known that GFR estimation based on creatinine and cystatin C (eGFR_cr-cys) is more accurate compared with estimated glomerular filtration rate (eGFR) based on either creatinine or cystatin C alone (eGFR_cr or eGFR_cys), but the incorporation of creatinine in eGFR_cr-cys needs specification of an individual's race, and beta-2-microglobulin (B2M) and beta-trace protein (BTP) represent alternative filtration markers that seem to be less impacted by race compared with creatinine, so, researchers used development and validation populations to compare panel eGFR using B2M and BTP in addition to cystatin C (three-marker panel) or creatinine and cystatin C (four-marker panel) with and without age and gender or race. They found that four-marker panel eGFR was as accurate as eGFR_cr-cys, without needing specification of race. A more precise race-free eGFR could represent a crucial advance.