Kim YC, et al. - Authors assessed the effectiveness and safety of ingenol mebutate gel for treating actinic keratosis (AK) of face/scalp and trunk/extremities in a large Asian (Korean) population. Experts, in this multicentre, open-label, interventional, parallel-group, prospective phase IV study, distributed the eligible patients into either the face/scalp or the trunk/extremities group, according to their selected treatment area location. On the application area, hyperpigmentation was seen in 7·8% subjects. None of the patients reported scars. Data demonstrated the effectiveness of Ingenol mebutate for the treatment of AK in Asians, with tolerable safety profiles.