Matsui Y, et al. - Twenty patients with rheumatoid arthritis (20 wrists) who underwent total wrist arthroplasty with the prosthesis in a clinical trial were recruited and analyzed by the researchers in order to assess the longitudinal clinical outcomes using a new semiconstrained wrist prosthesis for the treatment of severe rheumatoid arthritis of the wrist. No patient had wrist pain at the final follow-up. At final follow-up, the preoperative flexion-extension arc was comparable to the preoperative range. The mean 1.5-year postoperative Figgie score was significantly enhanced and was unaltered at final follow-up. The Disabilities of the Arm, Shoulder, and Hand (DASH) score significantly enhanced from prior to the surgery to 1.5 years following surgery and the DASH score was further enhanced at final follow-up, however, not significantly. Five of the 19 wrists assessed had radiographic findings suggesting carpal component loosening at final follow-up, however, all patients with the loosening had no symptom and had not undergone revision surgery. Thus, total wrist arthroplasty using this wrist prosthesis resulted in favorable clinical outcomes relative to pain relief and retained range of wrist motion.