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A longitudinal study on the prevalence and risk factors for depression and anxiety, quality of life, and clinical outcomes in incident peritoneal dialysis patients

Peritoneal Dialysis International Jan 31, 2019

Mok MMY, et al. - In patients beginning long-term peritoneal dialysis (PD) from March 2011 to April 2015, researchers assessed the quality of life (QOL) and the prevalence of and risk factors for depression and anxiety, as well as the change in these parameters over the first year of PD relative to clinical outcomes under the PD-first policy. They used the Hospital Anxiety and Depression Scale (HADS) and studied patient demographics and the incidence of hospitalization, peritonitis, exit-site infection, and all-cause mortality. The HADS was repeated after 9-12 months. At the start of PD, 39.6% of 191 patients had a high depression score, more commonly seen among diabetics. Also, 23.6% of overall patients had a high anxiety score; risk factors included younger age and diabetes. An inferior QOL, overall and across most QOL domains, was observed in association with both high depression and anxiety scores. No change was noted in the depression and anxiety symptoms in the first year of PD and these were not related to short-term clinical outcomes.

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