Agarwal R - In a cohort of 516 patients with chronic kidney disease (CKD), the researcher assessed age-related changes in body composition and its modification by sex and race. As controls, 45 healthy subjects were included. For up to 6 years, body composition was measured serially via air-displacement plethysmography. Loss of weight, body mass index (BMI), fat mass (FM) and fat-free mass (FFM), but not percent body fat (BF%) were strongly determined by older age (>60 years). On account of the loss of FFM and the accumulation of FM, no remarkable change in weight was observed in young black men, thereby masking obesity by conventional measurements. Overall, age, sex, and race had an impact on changes in body composition among CKD patients.