Tani S, et al. - The correlation between the changes in the serum eicosapentaenoic acid/arachidonic acid (EPA/AA) ratio linked to fish consumption and changes of the serum lipid levels in patients with one or more risk factors for atherosclerotic cardiovascular disease (ASCVD) was investigated in this hospital-based longitudinal study. The data presented in this work showed a high EPA/AA ratio, but not docosahexaenoic acid/AA ratio, derived from fish consumption, might lessen the risk of ASCVD via decreasing the risk of atherosclerosis development.