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A diagnostic evaluation of single screen testing for malaria in the returning traveler: A large retrospective cohort study

Academic Emergency Medicine Mar 08, 2021

Reynard C, Geary K, Chiodini P, et al. - Repeat testing is often required in screening for malaria in the returning traveler; however, audit data suggest that patients have not been reattending. Researchers here examined if this was safe, by determining the diagnostic efficacy of a single screen consisting of a rapid diagnostic test (RDT) and a thin film. In this retrospective cohort study, cases with suspected malaria who attended in the past 5 years were assessed from two large teaching hospitals. A total of 1,365 patients comprised the cohort. After excluding 33 patients who opted out of the research and one patient who did not have a complete initial screen, they assessed 1,331 screens. Among these, 74 were cases of Plasmodium falciparum (prevalence of 5.6%) and 104 of any malaria species (prevalence of 7.8%). Based on observations, they suggest a single thin film and RDT as likely sufficient as a first screen for falciparum malaria in the returning traveler with important caveats. They emphasize providing appropriate safety netting for those sent home from emergency departments.

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