Lavorini F, et al. – The present study aimed to compare cough sensitivity to inhaled tussigens, as well as spontaneous cough in response to the administration of zofenopril and ramipril in healthy volunteers; pharmacokinetic (PK) data of both zofenopril and ramipril, as well as their respective active forms, zofenoprilat and ramiprilat, was also collected. The results seemed to suggest that zofenopril has a more favourable profile when compared to ramipril as shown by a reduced pro–inflammatory activity and less effect on the cough reflex.