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A cross-sectional study on uric acid levels among Chinese adolescents

Pediatric Nephrology Jan 26, 2020

Lu J, Sun W, Cui L, et al. - By performing this cross-sectional survey in Shandong Province during 2017–2018, researchers determined the prevalence of hyperuricemia among adolescents. They performed this inquiry using multistage, stratified sampling method. They randomly sampled as well as examined 9,371 adolescents aged from 13 to 19 years. The overall mean serum uric acid (sUA) level was estimated to be 6.08 ± 1.57 mg/dL and overall hyperuricemia prevalence was reported to be 25.4% and 60.5% (when hyperuricemia was described as sUA ≥ 7 mg/dL or ≥ 5.5 mg/dL). In univariate and/or multivariate logistic regression analysis, the factors that were found to be related to an enhanced risk of hyperuricemia were: male gender, increased body mass index, increased waist circumstance, raised triglycerides, raised fasting blood glucose, raised systolic blood pressure, reduced estimated glomerular filtration rate, and positive family gout history. The reported sUA level and hyperuricemia prevalence in this adolescent population were found to be even higher compared with those of adults in China. A threat of gout attacks and other hyperuricemia-associated diseases may be posed by the epidemic of youth hyperuricemia.
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