Macey R, et al. - Authors analyzed 580 candidates, aged 18-52 years to compare the relationship and severity of fluorosis in adults with lifetime exposure to water fluoridation with a nonexposed specimen and also to report the gradient of fluorosis severity by age in fluoridated (Birmingham and County Durham) and nonfluoridated areas (Manchester) by using Thylstrup and Fejerskov (TF) scale. They observed the highest fluorosis in the youngest and lowest in the oldest age group with abate of the artistic influence of fluorosis with age.