Alsantali A - Researcher assessed the effectiveness of Eutectic Mixture of Local Anesthetics (EMLA) cream compared to ice application in alleviation of pain during botulinum toxin injections for palmar hyperhidrosis. The pain was evaluated using a Visual Analog Scale. Compared to the EMLA cream during Botox toxin injection for palmar hyperhidrosis, the successful use of ice application in reducing pain by 40% was noted. On the hands where EMLA cream was applied, the average pain score was 8.9, whereas it was 4.8 (±0.9) in the ice group.