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12-Month continuation of the etonogestrel implant in adolescents with polycystic ovary syndrome

Journal of Pediatric and Adolescent Gynecology Sep 16, 2020

Buyers E, Sass AE, Severn CD, et al. - Researchers sought to inscribe the reasons for choosing the etonogestrel (ENG) contraceptive implant among adolescents with polycystic ovary syndrome (PCOS). Further, they investigated the 12-month continuation rate and described the factors related to discontinuation. Retrospective chart review at a tertiary care children’s hospital between July 1, 2008 and August 30, 2019 yielded data of 96 patients with PCOS diagnosis confirmed per NIH criteria and ≥ 12-month ENG follow-up. Adolescents with PCOS showed good tolerability towards ENG implant and this was similar to published 12-month continuation rates. Documentation of reasons for ENG was observed for 74% (51% contraception, 32% ease of use, 15% other, 13% estrogen avoidance). Following were reported to be the main reasons for discontinuation: bleeding (41%), concern for weight gain (23%) and mood changes (18%). There was no independent predictive value of any of the preimplant characteristics for continuation, although 100% of patients with type 2 diabetes (N = 11) continued. Discontinuation was more frequent among patients who sought additional care including phone calls and clinic visits.

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