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Higher alcohol consumption leads to greater loss of muscle tissue in postmenopausal women

The North American Menopause Society News Jun 10, 2017

Both aging and menopause are known to affect sarcopenia, which is a loss of muscle mass and strength, which in turn affects balance, gait, and overall ability to perform tasks of daily living. A new study is one of the first to link alcohol consumption with a higher prevalence of sarcopenia in postmenopausal women.

The study outcomes were published online in the journal Menopause.

Previous studies of postmenopausal women have suggested the beneficial effect of estrogen therapy on muscle mass and function. Because of this, it is believed that postmenopausal women are more vulnerable to sarcopenia. Although alcohol is known to inhibit skeletal muscle protein synthesis, few studies have examined the relationship between sarcopenia and alcohol–drinking patterns.

The Korean–based study included 2,373 postmenopausal women (mean age, 62.4 y), 8.2% of whom were identified as having sarcopenia. Participants were categorized into three groups according to alcohol–drinking patterns, as assessed by the Alcohol Use Disorders Identification Test questionnaire.

Study results published in the article “Associations between high–risk alcohol consumption and sarcopenia among postmenopausal women” show that the prevalence of sarcopenia was found to be nearly four times greater for the high–risk, alcohol–drinking group than the low–risk group. High–risk drinking was determined by the self–reporting of quantity and frequency of alcohol consumption, combined with a perceived lack of control over drinking, as well as blackouts and other injuries related to drinking. Women in the high–risk, alcohol–drinking group were more likely to be current smokers and have worse blood pressure and total cholesterol. They were also significantly younger.
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