Thousands of COVID-19 survivors in the US are lining up to donate convalescent plasma to leading universities pushing forward with clinical trials in the race for solutions against the coronavirus pandemic until there's a vaccine to go around.
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"The ability to contribute to a cure was just an incredibly powerful experience," New York's very first donor of convalescent plasma to a Columbia University trial, told IANS. A single COVID-19 survivor, according to medical experts, could provide enough plasma in one sitting to treat two or three other patients. If they donate every seven days, as some in New York have begun doing, one person could donate 10 to 12 units of plasma in a month.
The donor said her first blood draw lasted 32 minutes. "I'm scheduled to go back tomorrow and every seven days for as long as I am allowed." The donor, who tested positive for COVID-19 on March 18, is the founder of Survivor Corps, a rapidly expanding grassroots movement in America that pools together plasma donors under a single umbrella.
The donor told IANS that she got infected with the COVID19 at a "professional type meeting" where there were eight people in all, fairly spaced apart and "there was no food involved and no touching". Of that group, seven were infected and one person has died. "So, for all the rules that suggest that gatherings under 10 are acceptable, this definitely flies in the face of that," the donor told IANS.
In her new role at Survivor Corps, the donor is advocating for stricter compliance with social distancing norms because "this virus is a mystery". "The best advice in terms of not getting the virus in the first place is just this: no one in, no one out, no exceptions. That's the best way," she said.
Doctors are calling the donor's plasma "liquid gold" because the donor not just recovered and donated plasma but is also a universal donor. "The donor cleared the virus and she made antibodies, and she made sufficient antibodies to clear that virus, and so we could potentially use that to help protect others with the disease," Dr. Eldad Hod, Associate Professor of Pathology and Cell Biology at Columbia University Irving Medical Center, told IANS.
Hod said randomised controlled trials were scheduled to begin this week, where 50 percent of patients will get convalescent plasma and the rest get non-convalescent plasma from people who donated before December. "That's the only way," he said, adding that "we're going to find out whether this works or not". Hod said more than 2,000 survivors are waiting to be screened at Columbia University alone.
The White House on April 15 confirmed that more than 45,000 people have recovered and urged these people to come forward and donate plasma. "People who have recovered from the corona virus have antibodies in your bloodstream, that can attack the virus. The Mayo Clinic on April 16 is working with the Red Cross to make sure that coronavirus patients have access to the convalescent plasma treatments and over 1000 institutions across America have already joined this program," the Vice President said at a press briefing on April 15.
The US death toll from the coronavirus currently stands at 30,844, with a total of 638,111 confirmed cases. The country now accounts for the highest number of cases and deaths in the world. The first of the Columbia University-led plasma trials are being done for health care workers on the frontlines with potential exposure to higher viral loads. Hod said Columbia is collaborating with Johns Hopkins University and Mayo Clinic on the trials. He hopes nurses, respiratory technicians, phlebotomists, and doctors could potentially be protected them by giving them convalescent plasma before they begin their work shifts.
Vaccine development is likely to take anywhere from 12-18 months, according to Dr. Anthony Fauci, America's top infectious diseases doctor.
