Edwards JD, et al. - In this longitudinal matched case-control study (2003–2013), researchers determined long-term adverse events risk for young stroke survivors with no early complications. They assessed a composite of death, stroke, myocardial infarction, and long-term or continuing care facility admission at 1, 3, and 5 years among consecutive patients with ischemic stroke or transient ischemic attack (young, ≤44 years) discharged from emergency or regional stroke centers in Ontario, Canada, with no death, recurrent stroke/transient ischemic attack, myocardial infarction, all-cause hospitalization, or admission to a long-term or continuing care facility (≤90 days) matched 10:1 to general population controls on age (±1 year), sex, income, geography, and case date (±50 days). A higher long-term hazard of adverse outcomes was seen among young stable stroke/transient ischemic attack survivors vs matched controls than older patients. Based on the results, long-term follow-up and aggressive risk reduction in young survivors as well as secondary prevention guidelines for these patients are required.