Boruta RJ, et al. - This trial probed into the longitudinal utility of speckle-tracking echocardiographic strain imaging as an early non-invasive marker, to screen for the development of Transplant coronary artery vasculopathy (TCAV). The results divulged that the variations in longitudinal (LS) preceded the catheterization-based diagnosis of TCAV in pediatric heart recipients. They appeared as early as one-year post-transplant. The within-subject LS changes displayed a potential utility as a non-invasive screening tool. This would aid in detecting those patients who were at increased risk for development of TCAV.