Yi Y, El Khoudary SR, Buchanich JM, et al. - This research sought to correlate the length of the reproductive period of women with type 1 diabetes (T1D) to women without diabetes. Researchers studied women with childhood-onset T1D (diagnosed in 1950-80) from the prospective Epidemiology of Diabetes Complications study and nondiabetic women from the Pittsburgh site of the Study of Women's Health Across the Nation (SWAN). Menopause status was evaluated using the historical and Women's Ischemia Syndrome Evaluation hormonal algorithms. In this study, women in the T1D cohort (n = 105) were younger, more likely to be White, never smokers, with lower BMI and higher high-density lipoprotein cholesterol levels matched with women without diabetes (n = 178). Compared with nondiabetic women, women with T1D onset before menarche have a shorter reproductive period, showing delayed menarche and earlier natural menopause. In addition, factors that may be related to a shorter reproductive period in T1D should be evaluated.