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Women with advanced pelvic organ prolapse and levator ani muscle avulsion would significantly benefit from mesh repair surgery

Ultrasound in Obstetrics & Gynecology Apr 12, 2021

Wong NKL, Cheung RYK, Lee LL, et al. - Via performing a prospective observational study of women who presented with Stage‐III or Stage‐IV pelvic organ prolapse (POP) and underwent primary prolapse surgery, researchers sought to determine the incidence of subjective and objective recurrence of POP following mesh repair surgery vs native‐tissue repair in these women. Among a total of 154 recruited women, 104 (67.5%) underwent mesh repair (transabdominal in 57 women and transvaginal in 47 women) and 50 (32.5%) had native‐tissue repair surgery. Outcomes revealed a 5‐fold reduction in the risk of subjective recurrence and a 6‐fold reduction in the risk of objective recurrence of prolapse among women undergoing mesh repair surgery, vs those undergoing native‐tissue repair. A 4‐fold decrease in both objective and subjective recurrence of POP was observed in women with concomitant levator ani muscle avulsion in correlation with undergoing mesh repair surgery. Overall low rate of mesh‐related complications was observed, and treatment of mesh exposure could be done conservatively or by minor surgery. Mesh surgery is thus suggested to offer benefit for these high‐risk women that seems to outweigh the risks of mesh complications, and hence, this group of women could be managed with this treatment option.

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