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Whole-body magnetic resonance imaging inflammation in peripheral joints and entheses in axial spondyloarthritis: Distribution and changes during adalimumab treatment

The Journal of Rheumatology Jan 12, 2020

Krabbe S, Eshed I, Sørensen IJ, et al. - Investigators sought to examine the distribution of whole-body magnetic resonance imaging (WB-MRI) inflammatory lesions of peripheral joints and entheses, and their response to adalimumab (ADA) treatment and agreement with clinical measures of disease activity in people with axial spondyloarthritis (axSpA). WB-MRI was conducted at weeks 0, 6, 24, and 48. In the acromioclavicular, metatarsophalangeal, and wrist joints, and at the greater trochanter, calcaneal insertion of the Achilles tendon, and ischial tuberosity, WB-MRI inflammatory lesions were noted frequently. It was found that inflammatory lesions of peripheral joints and entheses in individuals with predominantly axSpA, and variations therein, could be mapped utilizing WB-MRI. This may assist in differentiating inflammatory from noninflammatory joint tenderness.
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