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Whole-body diffusion-weighted MR and FDG-PET/CT in Hodgkin Lymphoma: Predictive role before treatment and early assessment after two courses of ABVD

European Journal of Radiology Apr 26, 2018

Albano D, et al. - Experts gauged if imaging features of pathologic lymph nodes on whole-body diffusion-weighted MR served a predictive role before treatment and could evaluate the response after 2 courses of chemotherapy in comparison to fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in patients with Hodgkin Lymphoma before and after 2 Doxorubicin-Bleomycin-Vinblastine-Dacarbazine (ABVD). It was discovered that interim-apparent diffusion coefficient (ADC) aided in detecting non-responder lesions. Nonetheless, size changes did not prove to be not useful. Baseline-SUVmax and ADC have no predictive role. Findings exhibited that bulky was the most useful imaging parameter to predict suboptimal response to chemotherapy.
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