Bian R, et al. - Experts pursued an investigaton of the neuromechanism underlying cognitive impairments of asthma. The proposition explored was that asthma patients exhibited altered white matter (WM) microstructures, which could contribute to their cognitive impairments. During this research, diffusion tensor imaging (DTI) covering the whole brain was acquired on a 3.0T scanner using a single-shot echo planar imaging sequence. Yielded data disclosed impairments of language ability, executive function, and visual-spatial processing and widespread WM disruptions reflected by fractional anisotropy (FA) reduction in asthma patients. Multiple cognitive impairments and universally WM integrity disruptions were illustrated in asthma patients, among which executive dysfunction exhibited a close connection with WM abnormalities.