Kilic C, Cakir C, Yuksel D, et al. - Researchers sought for clinical and pathological factors that may predict the parametrial involvement (PI) in early-stage cervical cancer. Inclusion of 406 patients with type III radical hysterectomy + pelvic ± para-aortic lymphadenectomy and FIGO stage I and II cervical adenocarcinoma, squamous type, and adenosquamous type cervical cancer was done. Lymphadenectomy was performed on the entire cohort of patients. Evaluation of early stage cervical cancer patients was done. Findings revealed independent prognostic value of lymph node metastases, LVSI, and surgical border involvement for PI in early-stage cervical cancer patients. This suggests the applicability of less radical surgical approaches for early-stage tumors with no nodal spread, negative LVSI, and no surgical border involvement.