Al Rayes H, et al. - Herein, the authors assessed the prevalence of Cognitive Dysfunction (CD) in SLE patients in studies that used a specified neuropsychological instrument. A high prevalence of CD was noted in the patients with lupus. They noted that the delay in the diagnosis of CD was complicated. Concerns were expressed by the caregivers and patients about cognitive function. However, testing for CD often imposed administrative and cost burdens. An unmet requirement for identifying the best screening, diagnostic metrics of CD was noted.