Hickey M, Moss KM, Krejany EO, et al. - Difficulties in sleep result in impairment of function and an increase in the risk of depression at menopause and sleep may further worsen because of premenopausal oophorectomy. In this prospective observational study, researchers quantified sleep quality prior to and up to 12 months after risk-reducing salpingo-oophorectomy (RRSO) compared these with measures recorded for a similar age comparison group who retained their ovaries. They performed evaluation of 95 premenopausal women undergoing RRSO and 99 comparisons over a 12-month period utilizing the Pittsburgh Sleep Quality Index (PSQI). Poor sleep quality was reported in almost half of the women at baseline. Findings revealed no effect of RRSO on overall sleep quality, however, they commonly identified new onset sleep disturbance, particularly in those with severe vasomotor symptoms. Based on findings, they recommend clinicians to be alert to new-onset sleep disturbance and the potential for HT to improve sleep quality.