Birch L, Perry R, Hunt LP, et al. - Researchers used meta-regression to determine the minimum change in BMI-SD score required to improve adiposity as percentage body fat for children and adolescents with obesity. They analyzed 39 studies, which reported on the change in mean percentage body fat. A mean reduction of percentage body fat mass was observed with reduction of at least 0.6 in mean BMI-SD score, in the sense that the associated 95% prediction interval for change in mean percentage body fat was wholly negative. Hence the success of interventions in reducing adiposity (a key purpose of weight management interventions) is demonstrated if they manifest reductions of 0.6 BMI-SD score.