Dewberry LC, Jalivand A, Gupta R, et al. - Researchers conducted a prospective cohort analysis to delineate changes in weight, cardiometabolic health, and weight-related quality of life (WRQOL) following adolescent LAGB. In the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS), data on demographic, anthropometric, micronutrient, cardiometabolic risk, and WRQOL were recorded from 242 adolescents. Data from 14 participants who underwent LAGB with 2 patients lost to follow-up were analyzed through 5 years. Mostly female (86%) and white (71%) comprised the participants; mean age was 18.2 ± 0.4 years; median BMI was 48.7 kg/m² (45.5–54.1). Preoperatively, elevated high sensitivity C-reactive protein (hs-CRP), dyslipidemia, elevated blood pressure (EBP), and type 2 diabetes (T2D) were prevalent in 100% (13/13), 62% (8/13), 57% (8/14), and 7% (1/14), respectively. Postoperative, 45% (4/11), 36% (5/11), 33% (4/12), and 0% (0/11) had the prevalence of hs-CRP, dyslipidemia, EBP, and T2D, respectively. The analysis revealed modest initial weight loss and improvements in cardiovascular risk factors with later weight regain and frequent need for band removal among these adolescents. Although the sample size was small, this prospective study revealed long-term outcomes with high rates of participant retention over time.