Tan J, et al. - Researchers sought to determine the link between warfarin use for atrial fibrillation (AF) treatment and risk of stroke, bleeding, and mortality in older adults on dialysis. They observed no difference in stroke risk, lower mortality risk in older end-stage renal disease patients with AF who were treated with warfarin, however, these patients had increased major bleeding risk. In addition, they noted that women vs men had a greater warfarin-associated bleeding risk. As per the observations, the risk/benefit ratio of warfarin may be less favorable among older women.