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Waist-to-height ratio and non-alcoholic fatty liver disease in adults

BMC Gastroenterology May 30, 2021

Sheng G, Xie Q, Wang R, et al. - Researchers herein used a large sample size to further explore as well as examine the relationship between waist-to-height ratio (WHtR) and non-alcoholic fatty liver disease (NAFLD) in adults. The study sample was from a large-scale health examination programme called ‘human dock’ in Japan. Among 14,125 participants, NAFLD prevalence was estimated to be 17.59%, with an average age of 43.53 ± 8.89 years. Per standard deviation increase in WHtR was related to a 66% increase in the NAFLD risk, following adjustment for all non-collinear covariables. Findings demonstrate an association of WHtR with NAFLD among adults, and the link was not purely linear but was shown to be non-linear, with significant threshold as well as saturation impacts.

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