Sood S, et al. – Researchers tried to find out the utility of whole brain radiotherapy (WBRT) applying volumetric–modulated arc therapy (VMAT) to spare the hippocampi and the aforementioned other organs at risk (OARs). This study illustrated the utility of WBRT using VMAT to not only spare the hippocampi, but also significantly reduce dose to OARs. It was demonstrated that these advantages of VMAT could potentially decrease the toxicities associated with NC–WBRT and improve patients' quality of life, particularly for patients with favorable prognosis receiving WBRT or patients receiving prophylactic cranial irradiation (PCI).