Vasconcellos LF, et al. - Early diagnosis of cognitive impairment in Parkinson's disease (PD) is essential due to its association with significant morbidity and mortality. Researchers assessed how useful magnetic resonance imaging (MRI) with automatic segmentation, such as FreeSurfer, could be in identifying those at higher risk of developing cognitive impairment. Clinical, neuropsychological and FreeSurfer variables that could have a relationship with worse cognitive outcomes over 18 months in PD patients were compared with controls. In the PD group, worse cognitive performance documented by neuropsychological assessment was connected with reduced volume of several structures by FreeSurfer analysis and could be a biomarker of cognitive decline.