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Volume of ropivacaine 0.2% and sciatic nerve block duration: A randomised, blinded trial in healthy volunteers

Acta Anaesthesiologica Scandinavica Oct 20, 2019

Christiansen CB, et al. - Researchers intended to determine if there is an association between the volume of ropivacaine 0.2% and sciatic nerve block duration. Sixty healthy volunteers were randomised to receive one of five volumes of ropivacaine 0.2%: 5, 10, 15, 20, or 30 ml. According to this randomised, double-blind trial, mean (SD) sensory block durations, defined as time of insensitivity to a cold stimulus, for the tibial nerve (TN) with increasing volume were: 9.3 h (1.7), 10.4 h (1.6), 9.7 h (2.9), 10.7 h (2.8), 9.9 h (2.6). For the common peroneal nerve(CPN), mean (SD) sensory block durations were: 10.6 h (2.7), 11.9 h (1.5), 11.0 h (3.3), 13.2 h (3.7), 13.5 h (6.1). On sensory sciatic nerve block duration, the authors discovered no impact of increasing the volume of ropivacaine 0.2% from 5 ml to 30 ml.
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