Ziada J, et al. - Authors sought to report the morphologic characteristics of the vitreomacular interface in intermediate age-related macular degeneration related to tangential traction due to premacular membrane formation and intended to associate with optical coherence tomography (OCT) findings and clinical data. In intermediate age-related macular degeneration, the fibrocellular premacular proliferation predominantly consisted of vitreous collagen, hyalocytes, and myofibroblasts with contractile properties. An important role was possibly played in traction formation of this subgroup of the eye by vitreoschisis and vitreous-derived cells. The release of traction by vitrectomy with internal limiting membrane peeling led to marked functional and anatomical improvement, in subjects having intermediate age-related macular degeneration and contractile premacular membrane.