Wang G, et al. - In this prospective birth cohort study, researchers determined how systolic blood pressure (SBP) in childhood is influenced by vitamin D trajectory through early life. Participants included 775 children who were followed prospectively up to age 18 years at the Boston Medical Center. A higher risk of elevated SBP at ages 3 to 18 years was reported in relation to low vitamin D status at birth vs sufficient vitamin D. A 1.59-fold higher risk of raised SBP at age 6 to 18 years was observed in relation to low vitamin D status in early childhood. In this study, an increased risk of elevated SBP during childhood and adolescence was found in relation to low vitamin D status and trajectory in early life.