Liu J, Wang W, Liu K, et al. - Experts aspired to explore whether VDR gene polymorphisms are correlated with psoriasis susceptibility and clinical response to calcipotriol in psoriatic patients. In total, 110 patients and 183 controls were genotyped for VDR gene polymorphisms rs2228570, rs731236, rs1544410 and rs7975232 by LDR method. Haplotype analyses demonstrated that the rs2228570/rs731236/rs1544410/rs7975232 CTGA was significantly over‐represented in patients with psoriasis compared with controls. Among the patients with PASI< 3, the response rates to calcipotriol were significantly greater in patients with rs7975232 CC genotypes compared with those with other genotypes. Such data indicate that VDR polymorphisms are related to psoriasis susceptibility and clinical response to calcipotriol in psoriatic patients.