Martucci G, Volpes R, Panarello G, et al. - Researchers conducted this prospective observational study to describe the trend of vitamin D in orthotopic liver transplantation (OLT) recipients and its association with outcomes. The sample consisted of 67 consecutive OLT recipients recruited between September 2016 and August 2017 at IRCCS-ISMETT, Palermo (Italy). A generalized linear mixed regression model examined the trend of vitamin D levels and potential factors affecting their levels. According to results, 64 (95.5%) recipients were vitamin D deficient (< 20 ng/ml), with a median value of 8.8 ng/ml, and 47 of these (70.1%) displayed severe deficiency (< 12 ng/ml) at baseline, 7.9 ng/ml. Preoperative Vitamin D and was highly associated with invasive infection in the first 28 postoperative days (PODs) and is correlated with disease severity. The value on POD 28 had a strong connection with graft function after OLT.