Taylor SN, et al. - Given that vitamin D supplementation is known to both prevent and treat rickets, a disease of hypomineralized bone, the researcher sought to analyze the role of vitamin D in toddlers, preschool children, and adolescents. Avoidance of rickets is correlated with pediatric vitamin D status. Randomized, controlled trials of vitamin D supplementation for pediatric bone health are minimal and deceptive in their findings. Beyond bone, a decreased risk for autoimmune, infectious, and allergic diseases was correlated with higher vitamin D status. The specific supplementation of vitamin D to optimize toddler, child, and adolescent outcomes is uncertain but doses 10–50 μg/day are safe and may be advantageous.