Kim RH, et al. - Vitamin D was demonstrated to promote the invasiveness of human extravillous trophoblasts (EVTs). However, whether vitamin D induces the epithelial-mesenchymal transition (EMT) of EVTs remains unclear. Researchers, herein, investigated if vitamin D promotes EMT and the related signaling pathways. Findings demonstrated that calcitriol served as a promoter of the invasive capability of EVTs by facilitating EMT induction and expression of MMPs via ERK signaling pathway.