Zhu Y, Wang Y, Gioia WE, et al. - This imaging study was sought to assess risk factors for prevalence and progression of aortic valve calcification (AVC) in lung cancer screening individuals and also to evaluate the sensitivity and reliability of visual AVCs on low-dose CT (LDCT) for predicting aortic stenosis (AS) in high-risk smokers. Between 2010 and 2017, researchers examined a total of 1,225 consecutive individuals in annual LDCT screening for lung cancer at Mount Sinai Hospital. The sensitivity and specificity of moderate/severe AVC scores on LDCT to distinguish AS on echocardiogram were estimated for 126 individuals who had both within 12 months. Risk factors for AVC at baseline, for progression, and for new AVC on annual rounds of screening were distinguished by using regression analyses. The results suggested that aortic valve calcification scores on LDCT should be documented, particularly in the lung cancer screening program.