Maul EJ, Kastner A, Schmidt J, et al. - Researchers conducted this retrospective observational study to evaluate the cumulative risk of progression in glaucomatous eyes in the severe stage of disease. In total, 143 eyes from 119 patients, were studied over a mean period of 4.9 ± 2.9 years. Data reported that the cumulative 5-year risk of progression estimated by Kaplan-Meier analysis was 14.6%. In severe glaucoma patients, the cumulative incidence of progression was found to be 2.9% per year in the first 5 years of follow-up. In other studies of glaucoma at various stages of severity, similar incidences have been reported.