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Visceral adipose tissue volume is associated with premature atherosclerosis in early type 2 diabetes mellitus independent of traditional risk factors

Atherosclerosis Oct 03, 2019

Reijrink M, de Boer SA, Spoor DS, et al. - In order to gain insights into the link between visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with premature atherosclerosis and (ie, arterial) inflammation, researchers examined the link between arterial 18F-fluordeoxyglucose (FDG) positron emission tomography (PET) uptake (a measure of arterial inflammation) and metabolic syndrome markers in early T2D patients. Participants were 44 patients having early T2D and were not on glucose lowering medication. The study sample had a median age of 63 [IQR 54–66] years and median BMI was 30.4 [IQR 27.5–35.8]). Findings revealed a positive link of CT-assessed VAT volume with FDG-PET evaluated arterial inflammation, independently of factors considered to potentially mediate these influences. In contrast to SAT, VAT was shown to be related to early atherosclerotic alterations in T2D patients.
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