Deschildre A, et al. - Researchers sought to compare the innate immune response and especially the expression of pattern recognition receptor (PRR) and their function in virus-infected and not-infected allergic asthmatic children, aged 6 to 16 years, admitted to hospital for a severe exacerbation. Among asthmatic children, a subgroup of patients prone to re-infection by virus exhibited a more pronounced impaired anti-viral response during virus-induced exacerbation. Altered PRR function and a different pattern of airway inflammation characterized this subgroup.