Allaire M, et al. - In the present study, researchers enrolled 389 cirrhotic patients treated by radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) within Milan criteria to define the main predictors of long-term overall survival (OS), including virologic control, and recurrence after RFA of HCC on cirrhosis. They evaluated relationships between patient features and events by the Kaplan-Meier method with the log rank test and using uni/multivariate Cox models. The main predictors of long-term OS after RFA for HCC developing on cirrhosis were virologic response and severity of the underlying liver disease.