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Very elderly patients with acute coronary syndromes treated with percutaneous coronary intervention

Heart, Lung, and Circulation Apr 28, 2021

Wong B, et al. - Among very elderly patients (≥85 years old) receiving percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS), this review was conducted to analyze their clinical characteristics as well as define factors related to adverse outcomes. This analysis involved 186 patients (mean age 87.6±2.8 years, 51.6% male). Overall 180 patients had a successful PCI. A maximal follow-up of 4 years revealed all-cause mortality and recurrent myocardial infarction rates of 22.0% and 14.0% respectively. An elevation in mortality risk was conferred by the presence of diabetes, ST-elevation myocardial infarction (STEMI), and decreased eGFR. In 14 patients, occurrence of major bleeding events while receiving dual antiplatelet therapy as defined by Bleeding Academic Research Consortium score ≥3 was seen. Findings revealed acceptable survival outcomes in very elderly patients who received PCI for ACS. Mortality in this elderly cohort was predicted by STEMI, diabetes and impaired kidney function.

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