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Vertebral fracture assessment in postmenopausal women with post-surgical hypoparathyroidism

Journal of Clinical Endocrinology and Metabolism Feb 15, 2021

Cipriani C, Minisola S, Bilezikian JP, et al. - A cross-sectional study was performed to assess the prevalence of vertebral fractures (VF) assessed by vertebral fracture assessment (VFA) in postmenopausal women with chronic post-surgical hypoparathyroidism. Researchers included a total of 50 postmenopausal women (mean age 65.4 ± 9 years) with chronic post-surgical hypoparathyroidism and 40 age-matched healthy postmenopausal women (mean age 64.2 ± 8.6). They assessed the lumbar spine, femoral neck, and total hip BMD by dual x-ray absorptiometry (DXA) (Hologic Inc., USA) in all subjects. Via TBS iNsight (Medimaps, Switzerland), site-matched spine TBS was estimated. Using the semiquantitative method and the algorithm-based qualitative assessment, evaluation of VF was made by VFA (iDXA, Lunar GE, USA). The results indicate for the first time that in postmenopausal women with chronic postsurgical hypoparathyroidism, VFs are demonstrable by VFA despite normal BMD.

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